A request for orientation


#1

Coming back into the game after 9 months of excruciating postdoc research, I haven’t the foggiest of what’s what. I bought the two “recent” DLCs, but would any kind soul orient me as to any major events, quests, tips thus far?
Anything would be greatly appreciated as I am getting mentally prepared to mount the challenge of hardcore gameplay.
Sincerely,
A layman