So far I’ve failed two quests since patch 1.3 and the common occurrence has been that there were cinematics immediately beforehand. The first was during the “Courtship” quest after taking Theresa to the tavern - the movie plays (dancing at the tavern and then being approached by the drunk) and immediately afterwards the quest failed. The second time was during “Nest of Vipers” when infiltrating the camp. The movie with Runt punishing one of his men played and right after it was done I failed the quest. I think this was a bug introduced with today’s patch as this didn’t happen to me before 1.3 came out.
** update ** I just started a new game on a different playline and as soon as the opening movie was finished I failed the first quest without even being able speak with Henry’s mother. When I try to click on her nothing happens.
** solution ** The error was being caused by a mod I was using that eliminated the various “Hey Henry!” greetings by NPC’s. After deleting it the problems stopped.