So right now I am in the midst of the quest line where you’re chasing down various members of the band that attacked the horse farm. On the tail end of finding ‘Reeky,’ despite the game telling me it was autosaving right before a scripted battle, save would corrupt and I would have to instead reload the previous save. After it did this a few times in a row, I opted to reload an even earlier save, and this time that autosave worked. Great!
Except after playing the game for another two hours, saving at least four times both using the special drink AND sleeping in the correct bed, I die during a later quest only to find out that every single save AFTER that autosave doesn’t work. They are not even in the list of saves at all, and selecting ‘Continue’ after death only brings up an error message. So just to be clear, I saved the game at least four times in the correct fashion, and the game somehow lost all of them.
Also here is another detail, not sure if this is normal or something to do with the bug, but on at least one occasion when I tried reloading with the continue option, the ‘Title/Death Screen’ background actually seemed to load the game itself, with and the UI and everything. It’s just obviously unplayable, as there’s no option to close THAT menu.
As someone who didn’t mind your design for the save system, this has pretty much taken the wind out of my sails. I don’t mind a certain degree of backtracking, but at this point I have no idea how to guarantee that a save file will actually stick, or if I will end up playing the game for 10 hours, saving regularly, only to lose a day’s progress because The game couldn’t manage a single successful save that entire time. 
Halp.